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However, the Drugs and Lactation Database (LactMed), a definitive resource on such matters, states that milk thistle is "unlikely to adversely affect the breastfed infant" and that it's "generally well tolerated in adults with only mild side effects.”21 Of course, no supplement is without its risks, so if you're considering milk thistle as a lactation aid, we recommend speaking with your doctor to confirm its suitability for you and your baby