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The instrument is inserted through the cervix, into the uterus, and allows the patient to be treated without incision or general anesthesia (Waltman 2011

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sTNF and its receptors sTNFR1 and sTNFR2 are pro-inflammatory molecules, the blood levels of which are associated with oxidative stress and are predictive of heart failure adverse outcomes [4], [6], [9], [11]