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Leonurine restrains granulosa cell ferroptosis through SLC7A11/GPX4 axis to promote the treatment of polycystic ovary syndrome - ScienceDirect

The compound interferes with S-adenosylmethionine (SAM) consumption, meaning it touches the same one-carbon methylation pool that governs DNA methylation and neurotransmitter synthesis, a biologically significant off-target risk that is underreported

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This includes choosing the appropriate injection site and rotating injection sites to avoid tissue damage or irritation