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They were randomly assigned to Sequence A or Sequence B, where Sequence A started with the GSH intervention followed by the placebo and Sequence B followed the opposite order

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As a master regulator of immune responses, the nuclear factor-κB (NF-κB) transcription factor complex governs the expression of numerous inflammation-related genes, including those encoding pro-inflammatory cytokines such as TNF-α and interleukin-6 (IL-6), as well as chemokines and adhesion molecules