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At the core of this transformation, RUNX1 emerges as a central modulator, coordinating transcriptional programmes that tie cellular plasticity directly to ECM remodeling

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Similarly, NAC’s antioxidant action and ability to modulate kinin B1 receptor expression may alleviate sensory polyneuropathy, hypertension and metabolic parameters associated with diabetes and insulin resistance, as diabetes mellitus is associated with depletion of cellular antioxidants and an increase in reactive oxygen species levels with resultant protein damage [14]