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Elevated cytokine levels might suppress telomerase activity, thereby limiting the enzyme’s ability to counteract telomere shortening and leading to cellular senescence ( 2.3.3 Interconnected dynamics of cellular aging: the telomere-mitochondrial axis Telomere shortening can disrupt normal cellular function and is implicated in the increased production of ROS, which further contribute to mitochondrial dysfunction and cell aging ( One proposed mechanism involves the tumor suppressor protein p53

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The examiner compares the involved wrist with the wrist on the other side