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Currently, studies have shown that compared to healthy individuals, patients with AD and chronic urticaria exhibit elevated levels of AOPPs (52)

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In addition, Scrophulariae Radix inhibits abnormal thyroid cell proliferation by activating the MST1/Hippo pathway while promoting apoptosis and autophagy ( Scrophulariae Radix modulates key urinary, hepatic, and serum metabolites, helping to correct hyperthyroidism-related metabolic disturbances ( Scrophulariae Radix significantly regulates phospholipid metabolites such as phosphatidylcholine and phosphatidylethanolamine, aiding in restoring lipid metabolism balance and preventing common lipid metabolic disorders in hyperthyroid patients ( Scrophulariae Radix significantly decrease key enzymes involved in glycolysis and the tricarboxylic acid cycle under hypermetabolic conditions ( Scrophulariae Radix in regulating glucose metabolism and inhibiting excessive metabolism ( Scrophulariae Radix affects lipid metabolism