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[41] showed increased oxidative DNA damage, as evaluated by measurement of urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels, compared with controls, in 8 patients with active GO who had been rendered euthyroid for at least 6 months with ATD therapy

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EPO is a glycoprotein hormone that, when released from the kidney, enhances the formation of red blood cells (erythropoiesis) in the bone marrow to increase the blood’s oxygen-carrying capacity [59]