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Traditional probiotics, such as Lactobacillus and Bifidobacterium strains, can sometimes overpopulate the small intestine in those with SIBO, making soil-based options a better-tolerated choice for some individuals

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[4] Human, topical, registered and ongoing: a trial of topical GHK-Cu gel (0.1% w/w) for acute skin wound healing versus vehicle gel in healthy adults was registered on ClinicalTrials.gov in 2026 (NCT07437586)