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Because this mechanism works within the body’s existing regulatory framework: Natural somatostatin feedback inhibition remains intact GH release follows physiological pulsatile patterns The pituitary gland is stimulated rather than suppressed Risk of supraphysiological GH levels is minimized Clinical Evidence for Sermorelin Sermorelin has a well-documented clinical history
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Kopetz, S , Grothey, A, Van Cutsem, E, Yaeger, R, Wasan, H, Yoshino, T, Desai, J, Ciardiello, F, Loupakis, F, Hong, YS, Steeghs, N, Guren, T, Arkenau, HT, Garcia-Alfonso, P, Belani, A, Zhang, X, Tabernero, J