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Being a cytoprotection mediator native and stable in human gastric juice, suggests its easy applicability, including the per oral route, and strong distinction from the standard angiogenic growth factors, whose effects regularly need carrier addition [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40]

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Cell Death Dis 2013;4:e626 [DOI] [PMC free article] [PubMed] [Google Scholar] 43.Ye D, Wang Y, Li H, Jia W, Man K, Lo CM, Wang Y, Lam KS, Xu A.Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1alpha-mediated antioxidant capacity in mice