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doi: 10.1515/znc-1995-5-619 24 GullnerG.TobiasI.FodorJ.KömivesT

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Statistical analysis Statistical significance was determined by the Student's t test or the one-way analysis of variance (ANOVA), with a threshold for significance set to p C:p.(Arg116Pro) that segregated with cortical malformations in three branches of a consanguineous family, and arginine at position 116 is extremely conserved down to Caenorhabditis elegans , suggesting that the novel DMRTA2 R116P mutation is the most likely cause of the phenotype (Fig