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Jastreboff et al., NEJM 2023)

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It is also a nutrient in muscle protein metabolism in response to infection, inflammation and muscle trauma.[1] Because of glutamine's importance as a nitrogen carrier and respiratory fuel for enterocytes of the gut and other rapidly proliferating cells, including lymphocytes and fibroblasts, glutamine can be considered as a conditionally essential amino acid.[2] Although there are no known drug interactions with glutamine, physiological antagonism may occur with lactulose when given to treat high ammonia levels in liver failures