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The role of N-acetylcysteine and glutathione in the management of Parkinson's disease: a systematic review of oxidative biomarkers and clinical outcomes | Amino Acids | Springer Nature Link

Introduction Mercapturic acids ( S -( N -acetyl)-l-cysteine conjugates) were first identified over 135 years ago and were soon recognized to play a role in the detoxification of certain halogenated xenobiotics (Bauman and Preusse, 1879)

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According to a 2022 United Nations Office on Drugs and Crime report, METH use has markedly increased, particularly in North America, East Asia, and Oceania, where it accounts for a significant proportion of stimulant-related drug abuse cases